A Single-Residue Switch for High Temperature Dependence of Thermal TRPV3 Channels
نویسندگان
چکیده
منابع مشابه
Single-residue molecular switch for high-temperature dependence of vanilloid receptor TRPV3.
Thermal transient receptor potential (TRP) channels, a group of ion channels from the transient receptor potential family, play important functions in pain and thermal sensation. These channels are directly activated by temperature and possess strong temperature dependence. Furthermore, their temperature sensitivity can be highly dynamic and use-dependent. For example, the vanilloid receptor tr...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2015
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2014.11.701